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    高级中间体

    Name

    Structure

    CAS No.

    阿托伐他汀钙中间体A5

    ethyl (R)-4-cyano-3-hydroxybutanoate

    141942-85-0

    阿托伐他汀钙中间体A6

    tert-butyl (R)-6-cyano-5-hydroxy-3-oxohexanoate

    125988-01-4

    阿托伐他汀钙中间体A7

    tert-butyl (3R,5R)-6-cyano-3,5-dihydroxyhexanoate

    125971-93-9

    阿托伐他汀钙中间体A8

    tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate

    125971-94-0

    阿托伐他汀钙中间体A9

    tert-butyl2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate

    125995-13-3

    阿托伐他汀钙中间体M4

    2-(2-(4-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenyl- pentanamide

    125971-96-2

    阿托伐他汀钙中间体L1

    tert-butyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate

    125971-95-1

    阿托伐他汀钙中间体L2

    tert-butyl (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenyl carbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

    134395-00-9

    阿托伐他汀钙L4API

    Atorvastatin Calcium

    134523-03-8

    瑞舒伐他汀钙中间体RSB-2

    methyl 4-(4-fluorophenyl)-6-isopropyl-2-oxo-1,2,3,4-tetrahydro- pyrimidine-5-carboxylate

    488798-36-3

    瑞舒伐他汀钙中间体RSB-3

    methyl 4-(4-fluorophenyl)-2-hydroxy-6- isopropyl- pyrimidine -5-carboxylate

    488798-37-4

    瑞舒伐他汀钙中间体RSB-4

    methyl 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)- pyrimidine-5-carboxylate

    289042-11-1

    瑞舒伐他汀钙中间体Z-7

    N-(4-(4-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

    147118-36-3

    瑞舒伐他汀钙中间体Z8.1

    N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

    289042-10-0

    瑞舒伐他汀钙中间体Z8.2

    Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me

    885477-83-8

    瑞舒伐他汀钙中间体D-4

    tert-butyl 2-((4R,6S)-6-(chloromethyl)-2,2-dimethyl-1,3- dioxan-4-yl)- acetate

    154026-94-5

    瑞舒伐他汀钙中间体D-5

    tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate

    154026-95-6

    瑞舒伐他汀钙中间体D-6

    tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3- dioxan-4-yl) acetate

    124655-09-0

    瑞舒伐他汀钙中间体D-7

    tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate

    124752-23-4

    瑞舒伐他汀钙中间体Z-8

    N-(4-(4-fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methyl- methanesulfonamide

    147118-37-4

    瑞舒伐他汀钙中间体R-1

    tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3- dioxane-4-acetate

    289042-12-2

    瑞舒伐他汀钙中间体R-2

    tert-Butyl rosuvastatin

    355806-00-7

    瑞舒伐他汀钙中间体H-1

    methyl (R,E)-3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6- isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept- 6-enoate

    147118-38-5

    瑞舒伐他汀钙中间体H-2

    7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino) pyrimidine -5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester

    147118-39-6

    瑞舒伐他汀钙中间体H-3

    methyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl) amino]-6-propan -2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate

    147118-40-9

    瑞舒伐他汀钙RSAPI

    Rosuvastatin Calcium

    147098-20-2

    匹伐他汀钙中间体N7

    (2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanol

    121660-11-5

    匹伐他汀钙中间体N7-Br

    3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline

    154057-56-4

    匹伐他汀钙中间体N8.1

    ((2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methyl)diphenylphosphine oxide

    146578-99-6

    匹伐他汀钙中间体P1

    tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

    147489-06-3

    匹伐他汀钙中间体P2

    tert-butyl (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate

    586966-54-3

    匹伐他汀钙中间体N8.2

    [2-Cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylmethyl]-triphenyl-phosphonium bromido

    154057-58-6

    匹伐他汀钙中间体N8

    2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde

    121660-37-5

    匹伐他汀钙中间体K2

    ethyl (E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylate

    2101241-52-3

    匹伐他汀钙中间体K3

    (E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)prop-2-en-1-ol

    1623109-08-9

    匹伐他汀钙中间体K4

    (E)-3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde

    148901-68-2

    匹伐他汀钙中间体K5

    ethyl (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-

    148901-69-3

    3-oxohept-6-enoate

    匹伐他汀钙中间体K6

    Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate

    172336-32-2

    477950-34-8

    匹伐他汀钙PI (API)

    Pitavastatin Calcium

    147526-32-7

    匹伐他汀钙中间体D-5

    tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate

    154026-95-6

    匹伐他汀钙中间体D-6

    tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3- dioxan-4-yl) acetate

    124655-09-0

    匹伐他汀钙中间体D-7

    tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate

    124752-23-4

    索弗布韦中间体SFA-9

    ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran- 2- yl) methyl benzoate

    874638-80-9

    索弗布韦中间体SFC

    isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

    1334513-02-8

    索弗布韦中间体SF-1

    (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy) methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate

    817204-32-3

    索弗布韦中间体SF-2

    ((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate

    863329-65-1

    索弗布韦中间体SF-3

    2'-deoxy-2'-fluoro-2'-C-methyluridine

    863329-66-2

    依折麦布中间体ZTM

    4-(((4-fluorophenyl)imino)methyl)phenol

    3382-63-6

    依折麦布中间体ZT-4

    (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5- dione

    189028-93-1

    依折麦布中间体ZT-5

    (S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2 -one

    189028-95-3

    依折麦布中间体ZT-6

    (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one

    272778-12-8

    依折麦布中间体ZT-7

    (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)-4-(4-((trimethylsilyl)oxy)phenyl)azetidin-2-one

    272778-13-9

    依折麦布中间体ZTB-7

    (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one

    190595-65-4

    依折麦布中间体ZTB-8

    4'-O-Benzyloxy Ezetimibe

    163222-32-0

    达比加群中间体DB-6

    ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)- 1H- benzo[d]imidazole-5-carboxamido)propanoate

    211915-84-3

    达比加群中间体DB-7

    1-methyl-2-[N-[4-amidinophenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide para-toluene sulfonate

    872728-85-3

    达比加群中间体DB-7-1

    ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole -5-carbonyl]-pyridin-2-ylamino] propanoate

    429658-95-7

    达比加群中间体DB-7-2

    ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride

    211914-50-0

    达比加群中间体DB-8

    ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl) amino) methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

    211915-06-9

    其他中间体DBP

    3-Pyridyldiethylborane

    89878-14-8

    其他中间体MDEB

    Methoxydiethylborane in THF

    7397-46-8

    其他中间体-3OT (S)-(+)-3-Hydroxytetrahydrofuran 86087-23-2
    EG4

    (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran

    915095-94-2
    EG4-Br

    (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran

    915095-89-5
    EG3

    (S)-(2-Chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone

    915095-87-3
    EG3-Br (5-bromo-2-chlorophenyl)-[4-[(3S)-oxolan-3-yl]oxyphenyl]methanone 915095-86-2
    EG2

    (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone

    915095-86-2
    EG2-Br

    (5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone

    915095-85-1
    EG1

    2-Chloro-5-iodobenzoic acid

    19094-56-5
    EG1-Br

    5-Bromo-2-Chlorobenzoic Acid

    21739-92-4
    S-3-羟基四氢呋喃(S3)

    (S)-(+)-3-Hydroxytetrahydrofuran

    86087-23-2

    溴吡喃葡萄糖Piv

    (EGM-Piv)

    [(2S,3S,4S,5R,6S)-6-bromo-3,4,5-tris(2,2-dimethylpropanoyloxy)tetrahydropyran-2-yl]methyl 2,2-dimethylpropanoate

    81058-27-7

    葡萄糖酸内酯TMS

    (EGM-TMS)

    (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)oxan-2-one

    32384-65-9
    高级中间体EG5-OMe

    (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol

    1279691-36-9

      

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